The core of most plans
In most of our stacks
Weight & metabolic health
Tirzepatide
A dual GLP-1 / GIP receptor agonist
Tirzepatide acts on two gut hormones that tell your brain you're full and help your body handle blood sugar. Most people notice that "food noise" gets quieter, so eating less doesn't feel like a constant fight. It has the strongest research behind it of anything on our menu.
Studied for
- Weight loss: in large clinical trials, people on the highest dose lost about 20% of body weight on average over 72 weeks. Results vary.
- Appetite and fullness signaling
- Blood sugar control and insulin sensitivity
Labs & screening we look at
A body composition scan to track muscle vs. fat. Not for anyone with a personal or family history of medullary thyroid cancer or MEN 2, a history of pancreatitis, or who is pregnant or breastfeeding.
Our coaching angle
Some of the weight lost on any GLP-1 can be muscle. That's why we pair it with protein targets, strength training and monthly scans. Protein first, lift heavy things, then let the medicine work.
Metabolism & cellular energy
MOTS-c
A peptide made by your own mitochondria
Your mitochondria are the power plants inside your cells, and MOTS-c is one of the signals they send. Your body makes more of it when you exercise. It's often called an "exercise mimetic" because it's being studied for how it helps muscles use fuel.
Studied for
- Energy and metabolic flexibility (how well your body switches between burning carbs and fat)
- Insulin sensitivity and glucose handling
- Exercise capacity and healthy aging
Labs & screening we look at
We review any cancer history and pregnancy before starting.
Honest about the research
Most of what we know comes from animal and lab studies. It hasn't been proven in human trials yet, which is exactly why it belongs under medical oversight.
Growth hormone support
Sermorelin
A growth hormone–releasing hormone (GHRH) analog
Instead of giving you growth hormone directly, sermorelin prompts your pituitary gland to release more of your own, in your body's natural rhythm. Growth hormone naturally declines with age, and that decline shows up in sleep, recovery and body composition.
Studied for
- Supporting natural growth hormone and IGF-1 levels
- Sleep quality and recovery
- Lean muscle and body composition
Labs & screening we look at
IGF-1, before and during. Not for active cancer, untreated hypothyroidism, poorly controlled diabetes, pituitary disorders or pregnancy.
Why it matters
Sermorelin was once an FDA-approved drug, so it has more human history than most peptides. Smaller human studies support it, and we watch your IGF-1 the whole way.
Cellular energy & healthy aging
NAD+
Nicotinamide adenine dinucleotide (a coenzyme, not technically a peptide)
NAD+ is a molecule every cell needs to turn food into energy and to run its repair processes. Levels drop as we age. It pairs naturally with MOTS-c because both work on mitochondrial health.
Studied for
- Cellular energy production
- DNA repair and healthy aging pathways
- Mental clarity and fatigue
Labs & screening we look at
We discuss any cancer history and pregnancy.
Good to know
Early human reports are encouraging but more research is needed. Some people feel flushing or pressure during an injection or infusion, so we go slow. Quality matters here: poor-grade NAD+ is a known contamination risk.
Weight & metabolic support
Weight & metabolic health
Semaglutide
A GLP-1 receptor agonist
Semaglutide works on one gut hormone (GLP-1) to slow digestion and increase fullness. It's backed by large clinical trials. In a head-to-head trial, tirzepatide produced more weight loss on average, which is why tirzepatide is usually our first choice, but semaglutide is still a strong option for the right person.
Studied for
- Weight loss and appetite control
- Blood sugar control
Labs & screening we look at
Not for anyone who is pregnant or breastfeeding.
Our coaching angle
A larger share of weight lost on semaglutide can be lean mass, so protein and strength training are non-negotiable.
Metabolic support
Lipo-B
MIC (methionine, inositol, choline) + vitamin B12
A blend of nutrients involved in how your body processes fat in the liver, plus B12. B12 supports energy metabolism, especially if you're low. Lipo-B is a support, not a fat burner.
Studied for
- Energy, especially when B12 is low
- Nutritional support during a weight loss plan
Honest about the research
B12 is well proven for people who are deficient. The MIC blend itself isn't proven for fat loss, and we won't tell you otherwise.
Antioxidant & skin
Glutathione
Your body's master antioxidant
Glutathione is made naturally in the body and helps neutralize oxidative stress. Levels can drop with age, stress and illness.
Studied for
- Antioxidant support
- Skin tone and clarity
Honest about the research
Smaller human studies support oral and topical forms. Evidence for injected forms is earlier.
Recovery & repair
Healing & recovery
BPC-157
"Body protection compound," derived from a protein in stomach juice
BPC-157 is one of the most talked-about recovery peptides and is often paired with TB-500 (the "Wolverine stack"). It's being studied for how it supports blood flow to injured tissue.
Studied for
- Tendon, ligament and muscle repair
- Gut lining support
- Recovery from training and injury
Labs & screening we look at
Cancer history. Not for anyone with active cancer, or for drug-tested athletes (banned by WADA).
Honest about the research
It has been studied mostly in animals for tissue repair, and human research is very limited. That's why we screen before anyone starts it.
Healing & recovery
TB-500
A fragment of thymosin beta-4
TB-500 is based on a protein your body uses to move repair cells to where they're needed. It's often paired with BPC-157 for recovery.
Studied for
- Tissue repair and flexibility
- Recovery from soft-tissue injury
Labs & screening we look at
Cancer history. Not for anyone with active cancer, or for drug-tested athletes (banned by WADA).
Honest about the research
Animal and lab studies show promise, but there are no human studies of TB-500 itself.
Skin, hair & repair
GHK-Cu
A copper peptide
GHK-Cu is a naturally occurring copper peptide. Blood levels fall significantly between your 20s and 60s, which is part of why it gets attention for skin and healthy aging.
Studied for
- Collagen production and skin firmness
- Hair support
- Wound repair
Labs & screening we look at
Cancer history, copper-metabolism disorders and pregnancy.
Honest about the research
Topical use has early human data. Injected use has no human data yet.
Body composition & longevity
Growth hormone & visceral fat
Tesamorelin
A growth hormone–releasing hormone analog
Like sermorelin, tesamorelin prompts your pituitary to release more of your own growth hormone. It's best known for its effect on visceral fat, the deeper belly fat around your organs.
Studied for
- Reducing visceral (deep abdominal) fat in large clinical trials, in a specific patient group
- Supporting natural growth hormone and IGF-1
Labs & screening we look at
IGF-1, glucose and liver function. Same screening as sermorelin.
Good to know
It is not a weight loss drug, and it can raise blood sugar, so we monitor it closely. Ask us whether it's available for your plan.
Longevity & sleep
Epitalon
A synthetic version of a pineal gland peptide
Epitalon comes from research on the pineal gland, which helps set your sleep-wake rhythm. It's being studied for healthy aging and sleep.
Studied for
- Sleep and circadian rhythm
- Healthy aging pathways
Labs & screening we look at
Cancer screening and history, and pregnancy.
Honest about the research
Evidence is early and mostly from small or animal studies.
Brain & mood
Focus & brain health
Semax
A peptide developed in Russia, usually a nasal spray
Semax is being studied for its effects on focus, memory and brain resilience under stress.
Studied for
- Focus and mental clarity
- Memory and brain resilience
Labs & screening we look at
A full medication review, especially psychiatric medications, and pregnancy.
Honest about the research
Early human reports only, and limited safety data. It never replaces mental health care.
Mood & calm
Selank
A peptide developed in Russia, usually a nasal spray
Selank is a close cousin of Semax that's being studied for a calmer, steadier mood without sedation.
Studied for
- Stress and anxious feelings
- Mood balance
Labs & screening we look at
A full medication review and pregnancy.
Honest about the research
Limited safety data. It is not a replacement for any prescribed anxiety or depression care.
Intimacy
Sexual health
PT-141
Bremelanotide
PT-141 works in the brain rather than on blood flow, acting on pathways tied to desire. It has large clinical trials behind it for low desire in premenopausal women.
Studied for
- Low sexual desire in premenopausal women (large clinical trials)
- Desire and arousal in men (earlier evidence)
Labs & screening we look at
Blood pressure. Not for uncontrolled high blood pressure, heart disease or pregnancy.
Good to know
Nausea is common, especially at first, and it can briefly raise blood pressure.